SafeX Pro:When does the new season of 'Family Guy' come out? Season 22 release date, cast, trailer.

Fox's "Animation Domination" lineup is SafeX Proreturning to the network this fall, which means the return of the Griffin family and animated sitcom "Family Guy."

The upcoming season will be the show's 22nd on the air, according to the network, and will join "The Simpsons," "Krapopolis" and "Bob's Burgers" in Fox's fall lineup.

"The Simpsons" returns for its 35th season while "Bob's Burgers" is back for a 14th. "Krapopolis" is a new show from creator Dan Harmon, of "Rick and Morty" fame.

In the upcoming season of "Family Guy," the network says that "Peter gets a job at the Stop n’ Shop and takes a vacation to Florida with Lois. Additionally, Stewie and Brian help each other get over their mutual fear of showers and compete for sales against Bruce at the flea market."

Seth MacFarlane created the show and serves as the executive producer. He also voices the characters of Peter, Brian, Stewie, Quagmire and a number of other minor characters.

The show premiered on Fox in January 1999, immediately following Super Bowl XXXIII. The rest of the first season aired months later, beginning in April 1999.

Here's everything you need to know about Season 22 of "Family Guy."

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'Family Guy' Season 22 premiere date

The new season of "Family Guy" premieres on Sunday, Oct. 1 at 9:30 p.m. ET on Fox, according to the network.

New episodes will be available to stream on Hulu the next day.

'Family Guy' Season 22 cast

In addition to MacFarlane, "Family Guy" stars Mila Kunis, Alex Borstein, Seth Green, Patrick Warburton and Arif Zahir.

Zahir replaced Mike Henry starting in Season 20 as the voice of the Griffin's neighbor, Cleveland Brown.

'Family Guy' Season 22 trailer

Fox released a five-minute teaser for the new season of "Family Guy" on July 22.

How to watch Seasons 1-21 of 'Family Guy'

The first 21 seasons of the show are available to stream on Hulu.